Rohto Pharmaceutical's popular eye drop series, "Rohto Z!" (ロートZ!), has a history of awesome collaborations with various anime and game IPs, always hitting it big with fans.
Now, they're teaming up with the iconic RPG series "Dragon Quest" for its 40th anniversary! Get ready for the limited-edition "Rohto Z! King Slime Eye Drops," hitting shelves across Japanese drugstores and e-commerce sites starting June 10, 2026.

Back in 2017, for Dragon Quest's 30th anniversary, the two brands dropped the original "Slime Eye Drops," which, as you can imagine, caused a massive stir. This third collaboration takes things up a notch, featuring the super popular monster, "King Slime," as the special edition bottle design.
With Dragon Quest celebrating 40 years, and Rohto Z! gearing up for its own 40th anniversary next year, the official word is they hope this partnership will make daily eye care more fun and invigorating, thanks to Rohto Z!'s signature super-refreshing sensation, especially for those tired eyes.

This epic crossover blends Dragon Quest's 40 years of adventure with Rohto Z!'s long history of bringing cool relief to weary eyes. And who better to help remind everyone about the importance of daily eye care than the beloved and adorable "King Slime"?
Plus, these three variants are inspired by Dragon Quest's very own ice spells, promising a super cool and refreshing experience!

The new bottle design looks just like the previous Slime eye drops evolved directly into a "King Slime." The overall shape perfectly captures King Slime's plump, iconic look, complete with a dazzling crown cap that truly gives it that "boss-level" vibe.
Even better, the capacity has been upgraded from the standard 12mL to a generous 16mL, making it last even longer.


▼ Inspired by the ice spell "Hyad" (ヒャド) 
▼ Inspired by the ice spell "Hyadalco" (ヒャダルコ)

▼ Inspired by the ice spell "Mahyad" (マヒャド)

Crack open the box, and you'll find a retro-style black-and-white battle scene hidden inside. Pop the King Slime eye drops onto the spot, and it transforms into that classic scene of "Slimes merging to form King Slime."
The official team even snuck in a few hidden Easter eggs, just waiting for DQ fans to discover them.

For modern folks glued to their phones, staring at computers, binging shows, and endlessly scrolling through social media, eye fatigue is practically a daily ritual. So, why not grab a King Slime to stand guard over your precious peepers?
Rohto Z! x "Dragon Quest" 40th Anniversary Collaboration
Release Date: June 10, 2026, available at major drugstores and other retailers across Japan.

via: ロート製薬: 商品情報サイト